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Team Award Winners: Infinite Possibilities Teams Awards
The 2021 MolecularCloud Distinguished Research Awards for outstanding research achievements in the genome-editing field. Team Award Winners – The Peer Dan Team- Infinite Possibilities Teams The lab is highly dynamic, multidisciplinary, and focuses on developing targeted vehicles for cell-specific delivery of novel molecular medicines using RNAi, mRNA, saRNA, DNA, and novel genome editing strategies. Our goal is to translate academic discoveries into innovative therapeutic mod
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Handbook of Harnessing Biomaterials in Nanomedicine Edited By Dan Peer
See our new edition of the handbook Harnessing Biomaterials in Nanomedicine, edited by Prof. Dan Peer. https://www.taylorfrancis.com/books/handbook-harnessing-biomaterials-nanomedicine-dan-peer/e/10.1201/9781003125259
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Design of mRNA vaccines delivered via novel lipid nanoparticles
ACS Nano 2020 Elia U, Ramishetti S, Rosenfeld R, Dammes N, Bar-Haim E, Somu Naidu G, Makdasi E, Yahalom-Ronen Y, Tamir H, Paran N, Cohen O, Peer D RNA vaccines are composed of mRNA, which encodes a disease-specific antigen, encapsulated in nanoparticles. When administrated to host cells, the RNA is translated into protein antigens that are recognized by the immune system and start a protective immune (cellular and humoral) response. In this study, we present the design of mR
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CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
Sci Adv. 2020 Nov 18;6(47):eabc9450 Daniel Rosenblum , Anna Gutkin , Ranit Kedmi , Srinivas Ramishetti , Nuphar Veiga , Ashley M Jacobi , Mollie S Schubert , Dinorah Friedmann-Morvinski , Zvi R Cohen , Mark A Behlke , Judy Lieberman, Dan Peer Harnessing CRISPR-Cas9 technology for cancer therapeutics has been hampered by low editing efficiency in tumors and potential toxicity of existing delivery systems. Here, we describe a safe and efficient lipid nanoparticle (LNP) for the
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