We aspire to utilize oligonucleotides loaded LNPs for in vivo reprograming of leukocytes and thus to design novel immunomodulatory therapeutic approaches for autoimmune disorders and cancer.

The goal of this project is to explore resistance pathways of cancer cells and translate the acquired knowledge by designing novel RNAi-based nanotherapeutics.

We aim to utilize RNA-loaded lipid nanoparticles in order to design new therapeutic modalities for various malignancies, including head & neck cancer, glioblastoma and breast cancer.

We aim to design novel platforms for a selective delivery of therapeutic payload to specific target cells, thus increasing the efficiency and reducing adverse effects.

This research aims to broaden the nanotechnology toolbox by designing new, highly efficient, methodologies for nucleic acids delivery.

LeukoTheranostics – Harnessing targeted nanotheranostics to reprogram activated leukocytes in inflammatory bowel disease.

Standwithus Original audio Another amazing Israeli innovation: Researchers from Tel Aviv University and the Israel Institute of Biological Research just paved the way for rapid vaccines against antibiotic-resistant superbugs that kill millions yearly around the globe. A small nation, a beam of light to the world. 🇮🇱💉

Congratulations to our Ph.D. Student, Lior Stosky Oterin, for receiving the Shmunis School Excellence Scholarship 2025 The Shmunis School Excellence Scholarship is an annual award presented by Tel Aviv University (TAU) to recognize outstanding young researchers in the fields of cancer and biomedical research. Established in 2020 through a generous donation from Vlad Shmunis and the Shmunis family, the prestigious award celebrates academic excellence among M.Sc. and Ph.D. grad

THE TIME OF ISRAEL, JULY 13, 2025 In a research breakthrough, scientists from Tel Aviv University and the Israel Institute for Biological Research (IIBR) in Ness Ziona have developed the world’s first mRNA-based vaccine against a deadly, antibiotic-resistant bacterium. The vaccine against pneumonic plague is delivered via lipid nanoparticles like COVID-19 vaccines, and showed a 100 percent protection rate in animal models. The groundbreaking study, which made the cover of the

The National Academy of Inventors (NAI) announced the election of 170 exceptional inventors into the 2024 Class of Fellows. NAI Fellowship is the highest professional. The 2024 cohort of Fellows exemplifies the Academy’s belief that groundbreaking innovation knows no bounds and inventors can be found everywhere. The 2024 Fellows hail from 135 research universities, governmental and non-profit research institutions worldwide and their work spans across various disciplines. The

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Dor Breier, Ph.D. student, receives the CBRC Weinstat Graduate Student Award for Cancer Research 2024 for his study, “Genome Editing Using Lipid Nanoparticles for Hepatocellular Carcinoma Therapy”.

TAU researchers induce cancer cell suicide with bacterial toxin. For the first time, scientists encoded a toxin into mRNA molecules and delivered them to cancer cells, causing the cells to produce the toxin that eventually killed them. The Jerusalem Post JULY 2, 2023 SCIENCE NEWS JULY 3, 2023 Many bacteria secrete toxins. The most famous of these is probably the botulinum toxin injected in Botox treatments. Another classic treatment technique is chemotherapy, involving the de

The National Academy of Engineering (NAE), has announced the appointment of Prof. Dan Peer from TAU as a Member of the Academy, in recognition of his groundbreaking research. JERUSALEM POST, FEB. 20, 2023 The National Academy of Engineering (NAE), one of the three National Academies in the USA (Sciences, Medicine, and Engineering), has announced the appointment of Prof. Dan Peer from Tel Aviv University, currently TAU’s VP R&D and Head of the Nanomedicine Lab at the Shmunis S

How do Vaccines Work? Enjoy our new manuscript for young minds. mRNA-LNP vaccines are injected into the muscle, where they are swallowed by muscle and immune cells. After entering the cells, the mRNA-LNPs release their mRNA molecules into the cell’s cytoplasm. In the cytoplasm, ribosomes “read” the code on the mRNA, using it to create the viral spike protein. When the spike protein breaks down inside cells, small pieces are moved to the cell membrane, where they are “shown” t

Eric Spitznagel, New York Post, Health, March 25, 2023. Scientists Edo Kon and Dan Peer from Tel Aviv University and the Israel Institute for Biological Research announced that they’d created a single-dose vaccine that could effectively protect people from Yersinia pestis bacterium. Haven’t heard of it? That’s because it’s better known (at least in the Middle Ages) as the plague — a disease that still kills thousands in Asia and parts of Africa each year. The plague might not

Researchers from Tel Aviv University and the Israel Institute for Biological Research have developed the world’s first mRNA vaccine effective against bacteria. By modifying proven mRNA technology used to fight COVID and other viral pathogens, the scientists developed a single-dose vaccine that fully protects mice against the Plague, the lethal disease that killed millions of people during the Middle Ages and is still around today, especially in parts of Africa and Asia. The r

Congratulation to our Ph.D. Students, Dana Tarab-Ravski and Lior Stotsky-Oterin for receiving the CBRC Excellent Achievements Prize in Cancer Research 2022.

Researchers from Tel Aviv University proved that a drug delivery system based on lipid nanoparticles can utilize RNA to overcome resistance to both chemotherapy and immunotherapy in cancer treatments. The study opens a new path to a personalized and precisely targeted battle against cancer. The results were published in the scientific journal Advanced Materials. The brand-new growth by Prof. Peer’s group constructs from one more current exploration: an enzyme called HO1 is ut